Sustainable Materials and Eco-Friendly Solutions in Transdermal Patch Development

Sustainable Materials and Eco-Friendly Solutions in Transdermal Patch Development

Twinkle Goyal1, Riya Dewangan1, Hema Rajwade1, Jigyasa Gupta1, Rishu Kumar2, Anjali Sahu2, Gyanesh Kumar Sahu2*

1Rungta Institute of Pharmaceutical Sciences

2Rungta Institute of Pharmaceutical Sciences and Research

ABSTRACT

A cutting-edge medication delivery method called a Transdermal patch is intended to administer therapeutic substances via the skin for a systemic impact. Transdermal patches, in contrast to conventional oral or injectable pharmaceuticals, enable a non-invasive, regulated, and prolonged release of medication. These patches have several benefits, such as better patient compliance, fewer side effects, and circumvention of the liver's first-pass metabolism. Numerous medications, such as hormones, painkillers, nicotine, and antihypertensives, are frequently delivered via these patches. A substrate layer, a drug storage of matrix-like, a rate-controlling the membrane itself, an adhesive layer, along with a protective liner make up the fundamental components of transdermal patches.Recent developments in transdermal technology, including smart patches, nanoparticles, and microneedles, have increased the range of possible uses for this drug delivery technique and made it possible to administer insulin, biologics, and even vaccinations. Additionally, the incorporation of detectors and surveillance systems into transdermal pads creates new opportunities for real-time health management and tailored medication. Notwithstanding these developments, issues such medication stability, skin permeability, and the requirement for patient-specific formulations still exist. Though the future is trending toward more effective, focused, and flexible therapies, transdermal patches remain a potential option for managing chronic diseases and delivering non-invasive therapeutics.