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ArticlePeer ReviewedOpen AccessPlagiarism Passed
Paper ID:IJSREMWP58752

A Review of UV-Visible Spectroscopy Analytical Technique

Stream/Area:

-

Subject:

-

Paper ID:

IJSREMWP58752

Volume:

10 |

3 |

Mar 2026

Pages:

Publication Frequency:

Monthly (12 issues per year)

DOI
Digital Object Identifier
Not assigned

License:International Journal of Scientific Research in Engineering and Management follows the Creative Commons Attribution 4.0 (CC BY 4.0) License, allowing free use and distribution with proper attribution.

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Authors

MVK

M. VENKATA KUMARI

MA

MD ARASLAAN

K

K.DADAKHALANDAR

MFA

MD FAISAL ALI

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Abstract

Treosulfan is an alkylating anticancer drug widely used in chemotherapy and conditioning regimens before hematopoietic stem cell transplantation. The present study aims to develop and validate a simple, accurate, and cost-effective UV-Visible spectrophotometric method for the estimation of Treosulfan in bulk and pharmaceutical dosage forms. Treosulfan shows maximum absorbance (λmax) at 258 nm using acetonitrile as the solvent. The method was validated according to ICH guidelines for parameters such as linearity, precision, accuracy, limit of detection (LOD), and limit of quantification (LOQ). The calibration curve showed good linearity in the concentration range of 2–12 µg/mL with a correlation coefficient close to 0.999. The developed method was found to be simple, precise, and suitable for routine analysis of Treosulfan in bulk drug and pharmaceutical formulations.

KEYWORDS

Treosulfan UV-Visible Spectroscopy Analytical Method Validation Bulk Drug Pharmaceutical Dosage Form.

Cite This Article

M. VENKATA KUMARI, MD ARASLAAN, K.DADAKHALANDAR, MD FAISAL ALI, "A Review of UV-Visible Spectroscopy Analytical Technique," International Journal of Scientific Research in Engineering and Management, vol. 10, no. 3, Mar 2026.

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Publication Date

3/20/2026

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Double-Blind Peer Review

Review Rounds: 2

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