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ArticlePeer ReviewedOpen AccessPlagiarism Passed
Paper ID:IJSREM59395

A Review on Analytical Approaches for Dapagliflozin, Gliclazide and Metformin: Reverse Phase HPLC.

Stream/Area:

-

Subject:

-

Paper ID:

IJSREM59395

Volume:

10 |

4 |

April 2026

Pages:

Publication Frequency:

Monthly (12 issues per year)

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Not assigned

License:International Journal of Scientific Research in Engineering and Management follows the Creative Commons Attribution 4.0 (CC BY 4.0) License, allowing free use and distribution with proper attribution.

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Authors

SKS.

Sonu Kumar Sandilya .

DMB

Dr. Mukesh Bansal

DDA

Dr. Dilip Agrawal

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Abstract

This study presents analytical methodologies for the determination of Dapagliflozin, Gliclazide and Metformin, employing reverse-phase high-performance liquid chromatography (RP-HPLC) and UV spectroscopy. The RP-HPLC method utilizes a C18 column and a mobile phase comprising acetonitrile and phosphate buffer, demonstrating high specificity and precision. UV spectroscopy involves the measurement of absorbance at a wavelength of maximum absorption. Both methods exhibit excellent linearity, accuracy, and sensitivity for Dapagliflozin, Gliclazide and Metformin, quantification. These validated techniques offer reliable tools for pharmaceutical quality control, ensuring accurate dosage assessment and potency evaluation in formulations containing Dapagliflozin, Gliclazide and Metformin.

KEYWORDS

Chromatography HPLC and UV spectroscopy Instrumentation Applications Methodology

Cite This Article

Sonu Kumar Sandilya ., Dr. Mukesh Bansal, Dr. Dilip Agrawal, "A Review on Analytical Approaches for Dapagliflozin, Gliclazide and Metformin: Reverse Phase HPLC.," International Journal of Scientific Research in Engineering and Management, vol. 10, no. 4, April 2026.

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Publication Date

8/3/2026

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Double-Blind Peer Review

Review Rounds: 2

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The authors declare no conflict of interest related to this research work.

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