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Stream/Area:
-
Subject:
-
Paper ID:
IJSREM65070
Volume:
10 |
6 |
Jun 2026
Pages:
1-8
Publication Frequency:
Monthly (12 issues per year)
License:International Journal of Scientific Research in Engineering and Management follows the Creative Commons Attribution 4.0 (CC BY 4.0) License, allowing free use and distribution with proper attribution.
Pharmacy
Guru Kashi University ,Talwandi Sabo, Bathinda
Brain cancer is a serious disease, especially a kind called glioblastoma multiforme. People with this disease usually do not live long only about 15 to 20 months even when they get very strong treatments. Major problem is that there is a wall around the brain called the blood-brain barrier that stops delivery of medicines into brain. This creates difficulties to treat brain cancer with medicines. In the few years scientists have been looking at using tiny things called carbon nanotubes to deliver medicines to the brain. These things are very good at carrying medicines because they have a surface area and are very strong. They can also be changed in ways to make them work better and advancement in treatment. This article looks at all the ways that carbon nanotubes are being used to treat brain cancer. The nanotubes work better how to get them past the blood-brain barrier and how to use them with other treatments. Discuss concerns, about safety what the government says about using these treatments and new technologies that might help get these treatments to people. Brain cancer and carbon nanotubes are the focus of this article.
KEYWORDS
Clinically, glioblastoma (GBM) is one of the most aggressive and challenging brain tumors. It is highly heterogeneous, invasive and spread throughout the brain. The aggressive interactions with the surrounding tissues and the presence of the blood-brain barrier limit the efficacy of traditional chemotherapy. Nanocarriers based on carbon nanotubes (CNT) can help overcome the presence of barriers, chemical heterogeneity and offer a high degree of formation and configuration of the polymeric matrix and control of the drug delivery system. CNTs can modify the BBB using receptor-mediated transport, transcytosis, and other mechanisms of delivery. Furthermore, the modification of CNT with targeting ligands, e.g. peptides, antibodies, folic acid and transferrin, allows selective transport and reduces unwanted effects for glioblastoma. CNTs can also be used for transport and delivery of various pharmaceuticals, and offer a multifunctional system toward the theranostic application for GBM. Future research can synthesize biocompatible CNTs and develop personalized nanocarriers for treatment. The carriers can contain various combinations of stimuli-activated therapies. The efficacy of the carriers should be tested in preclinical and clinical studies.Advances in nanotechnology, molecular targeting, and precision medicine are expected to further enhance the therapeutic potential of CNT-based systems for glioblastoma.
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Publication Date
6/17/2026
Peer Review Type
Double-Blind Peer Review
Review Rounds: 2
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