A Review on Enteric Coated Granules

Enteric coated granules are solid unit dosage forms intended for oral administration that are engineered to bypass the stomach and release the drug into the small intestine. “enteric” indicates small intestine; As a result, enteric coatings stop medication from being released before it reaches the small intestine. The majority of enteric coatings function by providing a coated surface that is stable at the stomach’s highly acidic pH but rapidly degrades at a less acidic (relatively more basic) pH. These materials include fatty acids, waxes, shellac, plastics, and plant fibers. The ideal properties of enteric coatings, their advantages and disadvantages, the various polymers used, their chemical structures, the selection and mechanism of drugs, and the manufacturing and evaluation of enteric coated granules are all covered in this review. Due to their advantages over conventional drug delivery systems—longer dosing intervals and increased patient compliance—these have recently piqued the interest of numerous formulators. The study provides an overview of the most recent developments in this field.