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ArticlePeer ReviewedOpen AccessPlagiarism Passed
Paper ID:10.55041/IJSREM38362

A Review on High Pressure Liquid Chromatography

Stream/Area:

-

Subject:

-

Paper ID:

10.55041/IJSREM38362

Volume:

8 |

11 |

Nov 2024

Pages:

Publication Frequency:

Monthly (12 issues per year)

DOI
Digital Object Identifier
10.55041/IJSREM38362

License:International Journal of Scientific Research in Engineering and Management follows the Creative Commons Attribution 4.0 (CC BY 4.0) License, allowing free use and distribution with proper attribution.

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Sonali Shivaji Mirkut

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Abstract

High performance liquid chromatography (HPLC) has a dominant position among the Modern techniques in both the qualitative and quantitative drugs analysis. After adequate Sample preparation it is also commonly used for the determination of drugs and metabolites in Biological material.This study is focused on the development and validation of a chromatographic Method suitable for the analysis of 2’,4’-dihydroxyacetophenon isonicotinoyl hydrazone (DHAP-INH) – a novel biocompatible iron chelator, and its application for stability Evaluation of this drug candidate in rabbit plasma in vitro. DHAP-INH is among newly Synthesized salicylaldehyde isonicotinoyl hydrazone (SIH) analogues, which were prepared to Improve compound stability in plasma and thus make pharmacokinetic profile of Aroylhydrazones more favorable.

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Cite This Article

Sonali Shivaji Mirkut, "A Review on High Pressure Liquid Chromatography," International Journal of Scientific Research in Engineering and Management, vol. 8, no. 11, Nov 2024. https://doi.org/10.55041/IJSREM38362

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4/10/2024

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