A Review on Non -Aqueous Nano Emulsion

Generally emulsions are water-in-oil or oil-inwater type, but emulsions may contain polar liquid as one of the phase. Non-aqueous nano-emulsions are useful in many situations where presence of water is not desirable, and formulation of active ingredients which undergo hydrolysis or oxidation in the presence of water. The non-aqueous nano emulsion subject to design a stable non-aqueous nanoemulsion (NANE) using cosmetically approved ingredients as a vehicle for the water-sensitive active ingredients. Non-aqueous nanoemulsion subject to increase the dermal penetration and permeation and study solubility and dermal bioavailability of drug. For better compliance, the non-aqueous nano emulsions will be incorporated in cosmetics or personal care products. A non-aqueous system was obtained with glycerin and olive oil stabilized by glycerol monosterate with co-surfactant. It was observed that emulsification behavior is completely unpredictable and conventional theories of emulsification and HLB system cannot be applied here. An optimized non-aqueous nano-emulsion is obtained through implementation of pseudo- ternary phase curve. Non-aqueous nano-emulsion region is determined and further characterized for pH, rheology, globule size analysis, zeta potential and stability. [1]