Loading article...
Loading article...
Stream/Area:
-
Subject:
-
Paper ID:
10.55041/IJSREM.RACCES019
Volume:
10 |
4 |
April 2026
Pages:
1-5
Publication Frequency:
Monthly (12 issues per year)
License:International Journal of Scientific Research in Engineering and Management follows the Creative Commons Attribution 4.0 (CC BY 4.0) License, allowing free use and distribution with proper attribution.
Department of Artificial Intelligence and Data Science
Bharathiyar Institute of Engineering for Women(Autonomous),Salem, Tamilnadu, India
Department of Artificial Intelligence and Data Science
Bharathiyar Institute of Engineering for Women(Autonomous),Salem, Tamilnadu, India
Department of Artificial Intelligence and Data Science
Bharathiyar Institute of Engineering for Women(Autonomous),Salem, Tamilnadu, India
Department of Artificial Intelligence and Data Science
Bharathiyar Institute of Engineering for Women(Autonomous),Salem, Tamilnadu, India
Leukemia, a bone marrow-related disease, arises from the abnormal proliferation of cells. It is the predominant form of childhood cancer, representing about one-third of cases annually. This study focuses on incorporating AI models to enhance the early detection of Leukemia.This research reviews deep learning methodologies for detecting leukemia, a critical cancer diagnosis and treatment aspect. Using a systematic mapping study (SMS) and systematic literature review (SLR), thirty articles published between 2019 and 2023 were analyzed to explore the advancements in deep learning techniques for leukemia diagnosis using blood smear images. The analysis reveals that state-of-the-art models, such as Convolutional Neural Networks (CNNs), transfer learning, Vision Transformers (ViTs), ensemble methods, and hybrid models, achieved excellent classification accuracies. Preprocessing methods, including normalization, edge enhancement, and data augmentation, significantly improved model performance. Despite these advancements, challenges such as dataset limitations, the lack of model interpretability, and ethical concerns regarding data privacy and bias remain critical barriers to widespread adoption .The review highlights the need for diverse, well-annotated datasets and the development of explainable AI models to enhance clinical trust and usability. Additionally, addressing regulatory and integration challenges is essential for the safe deployment of these technologies in healthcare.
KEYWORDS
This paper provides insights from a systematic mapping study (SMS) and a systematic literature review (SLR) focused on deep learning techniques for leukemia diagnosis. By analyzing thirty studies, the review highlights a variety of methodologies that demonstrate promising levels of accuracy and sensitivity in detecting leukemia from blood smear images. The findings emphasize the importance of ongoing research to overcome current challenges and enhance the development of deep learning models that are accurate, reliable, and interpretable. Such advancements are essential for improving patient care and supporting informed decision-making in clinical settings. Integrating large language models (LLMs) into healthcare systems holds great potential to further transform diagnostics and treatment. LLMs’ ability to adapt to evolving data and contexts can drive advancements in disease prediction, personalized care, and operational efficiency. However, addressing challenges like dataset limitations, ethical concerns, and practical implementation hurdles is critical to successfully adopting these technologies. With continued innovation and interdisciplinary collaboration, AI and machine learning can significantly reshape healthcare delivery, leading to improved outcomes and more equitable access to care. This paper highlights the potential of AI models in revolutionizing medical diagnosis and treatment. Significant progress has been made in improving healthcare facilities by utilizing the machine learning algorithms and more recent deep learning algorithms. It has opened the doors for precise and effective analysis of medical images helping in early identification of diseases like leukemia that we worked on in our project. Specially, ViT-B16, i.e., vision transformers, have a capability for medical image analysis with special benefits because of their ability to capture spatial relationships and global context in images. Moreover, our user-friendly graphical user interface has further expanded the possibilities for medical workers to identify diseases in seconds, making it a valuable tool for healthcare professionals. The promising results obtained from the vision transformer in leukemia detection suggest its potential for use in future diagnostic tasks in the field of medical and healthcare. For future work, our user interface can be further transformed into web application for professional use in healthcare. It can be progressed further by keeping main focus on getting relatively larger and diverse dataset that can enhance accuracy and performance of the model significantly for this purpose various data augmentation techniques can be utilized.
1.Robert W Miller, John L Young Jr, and BiljanaNovakovic, “Childhood cancer,” Cancer, vol. 75, no. S1, pp. 395–405, 1995. 2.Nizar Ahmed, AltugYigit, ZerrinIsik, and AdilAlpkocak, “Identification of leukemia subtypes from microscopic images using convolutional neural network,” Diagnostics, vol. 9, no. 3, pp. 104, 2019. 3.Rodrigo Veras, Andre Santana, Jo ´ ao Tavares, ˜ Justino Santos, and Vinicius Machado, “Convolution neural network models for acute leukemia diagnosis,” in 2020 International Conference on Systems, Signals and Image Processing (IWSSIP). IEEE, 2020. 4.Fatichah, C. Identification of acute lymphoblastic leukemia subtypes in touching cells based on enhanced edge detection. Int. J. Intell. Eng. Syst. 2020 5. De Sant, Y.F.D. Lightweight Classification of Normal Versus Leukemic Cells Using Feature Extraction. In Proceedings of the 2021 6.Suciati, N. Deep Learning for the Detection of Acute Lymphoblastic Leukemia Subtypes on Microscopic Images: A Systematic Literature Review. IEEE Access 2023 7. G Meena Devi and V Neelambary, “Computer-aided diagnosis of white blood cell leukemia using vgg16 convolution neural network,” in 2022 4th International Conference on Inventive Research in Computing Applications (ICIRCA). IEEE, 2022
Publication Date
5/2/2026
Peer Review Type
Double-Blind Peer Review
Review Rounds: 2
Documents
Article Views
1
Total views since publication
PDF Downloads
6
Total downloads since publication
Geographic Reach
5
Digital Preservation: This article is permanently archived on Zenodo and complies with all data preservation standards across major indexing platforms.
Plagiarism Screening
This manuscript has been checked for plagiarism using TurnitinPlagiarismChecker software.
Conflict of Interest
The authors declare no conflict of interest related to this research work.
Funding Information
No funding information available for this research.
Related research in the same subject area
Loading similar articles...