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Paper ID:10.55041/IJSREM.RACCES013

Al Driven Deep CNN Framework for colorectal Disease Diagnosis for Histopathological image datasets - (multi-class colorectal diseases diagnoses Explainable Grad (AMMTT))

Stream/Area:

-

Subject:

-

Paper ID:

10.55041/IJSREM.RACCES013

Volume:

10 |

4 |

April 2026

Pages:

1-5

Publication Frequency:

Monthly (12 issues per year)

DOI
Digital Object Identifier
10.55041/ijsrem.RACCES013

License:International Journal of Scientific Research in Engineering and Management follows the Creative Commons Attribution 4.0 (CC BY 4.0) License, allowing free use and distribution with proper attribution.

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Authors

R

Revathi.R

Artificial Intelligence & Data Science

Bharathiyar Institute of Engineering for Women(Autonomous),Salem, Tamilnadu, India

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P

Prathiba.S

Artificial Intelligence & Data Science

Bharathiyar Institute of Engineering for Women(Autonomous),Salem, Tamilnadu, India

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T

Thilainayagi.N

Artificial Intelligence & Data Science

Bharathiyar Institute of Engineering for Women(Autonomous),Salem, Tamilnadu, India

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D

Divya.S

Artificial Intelligence & Data Science

Bharathiyar Institute of Engineering for Women(Autonomous),Salem, Tamilnadu, India

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Abstract

Colorectal cancer is one of the leading causes of cancer-related deaths worldwide. Early and accurate diagnosis is essential for improving patient survival and treatment outcomes. Traditionally, histopathological examination of tissue samples by pathologists is considered the standard method for diagnosing colorectal diseases. However, this manual process is time-consuming and depends heavily on expert knowledge, which may lead to variations in diagnosis. In this project, an AI-driven Deep Convolutional Neural Network (CNN) framework is proposed for the automatic detection and classification of colorectal diseases using histopathological images. The proposed system performs multi-class classification to identify different types of tissue patterns such as normal tissue, adenoma, cancerous tissue, inflammation, and necrosis. A pretrained CNN model like ResNet50 is used for feature extraction to improve the model's performance and accuracy. To enhance transparency and reliability in medical diagnosis, an explainable AI technique called Grad-CAM++ is integrated into the system. Grad-CAM++ generates heatmaps that highlight the important regions in histopathological images responsible for the model’s predictions, allowing pathologists to visually interpret and verify the decision-making process. The proposed framework aims to assist medical professionals by providing faster, more accurate, and explainable diagnostic support for colorectal disease detection .

KEYWORDS

Key Words:Artificial Intelligence (AI) Deep Learning Convolutional Neural Network Histopathological Image Analysis Multi-class Classification Explainable Artificial Intelligence (XAI) Grad-AMM – TT Medical Image Processing Colorectal cancer Detection.

Cite This Article

Revathi.R, Prathiba.S, Thilainayagi.N, Divya.S, "Al Driven Deep CNN Framework for colorectal Disease Diagnosis for Histopathological image datasets - (multi-class colorectal diseases diagnoses Explainable Grad (AMMTT))," International Journal of Scientific Research in Engineering and Management, vol. 10, no. 4, pp. 1-5, April 2026. https://doi.org/10.55041/ijsrem.RACCES013

Full Article/Conclusion

The proposed deep learning model was trained and tested using histopathological image datasets of Colorectal cancer. The CNN model successfully extracted important features from the images and performed multi-class classification with high accuracy.   The experimental results show that the proposed system improves classification performance compared to traditional methods. The Grad-AMM-TT technique also generated clear attention maps that highlight the important regions in the images. These visual explanations help medical experts understand the model’s decision process.   Overall, the results demonstrate that the proposed system can support pathologists by providing faster and more reliable disease diagnosis.

References

1.      Alex Krizhevsky,Ilya Sutskever, and Geoffrey Hinton(2012). ImageNet Classification with Deep Convolutional Neural Networks. Advances in Neural Information Processing Systems.   2.      Karen Simonyan and Andrew Zisserman (2014). Very Deep Convolutional Networks for Large-Scale Image Recognition.     3.      Kaiming He, Xiangyu Zhang, Shaoqing Ren, and Jian Sun (2016). Deep Residual Learning for Image Recognition. . 4.      Ramprasaath R. Selvaraju et al. (2017). Grad-CAM: Visual Explanations from Deep Networks via Gradient-based Localization.   5.      World Health Organization (2023). Cancer and Colorectal Disease Global Statistics Report.     6.      National Institutes of Health (2022). Histopathological Image Analysis Using Deep Learning.  

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Publication Date

5/1/2026

Peer Review Type

Double-Blind Peer Review

Review Rounds: 2

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