An Efficient One-Pot Synthesis of 2, 3-Dihydro-2-Phenyl-1H-Naphtho[1, 2-e][1, 3]oxazine derivatives using L-Cysteine as catalyst

In conclusion, we have developed efficient and environmentally benign methodology for the synthesis of 2, 3-dihydro-2-phenyl-1H-naphtho-[1, 2-e] [1,3]oxazines derivatives by a one-pot, Multicomponent reaction from cyclocondensation of 2-naphthol, formalin and aromatic amines and under stirring in ethanol at room temperature in the presence of L-cysteine. The advantages of this method over other existing methods are reduced reaction times, higher yields, mild reaction condition, easy purification, non-hhazardous and economic viability of the catalyst. We feel that this economically viable procedure will find practical utility for the one pot synthesis of novel [1,3]oxazines derivatives.

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