Benefits Of Ketamine Versus Propofol in Acute Traumatic Brain Injuries with Elevated Intracranial Pressure

Ketamine has been used as an anesthetic drug over 65 years. Ketamine is a potent analagesic with dissciative and sedative properties. In early research Ketamine should not be administered to those with acute brain injuries. In(1970) early studies suggesting that it could increases the pressure inside the skull known as intracrainal pressure and thus a decreases in cereberal perfusion and reduce oxygen supply to the demaged cerebal cortex. Current studies has shown that ketamine directly evaluating the effect of patient on ICP in traumatic brain injury I.e decreases ICP. Ketamine now considerd one of the best drug because provide excellent hemodynomic support. In comparison, the use of propofol for induction is one of the most popular agent used for induction of anesthesia and long term sedation. Propofol, a short acting intravenous anesthetic , has been utilized in the management of craniocerebral injury for induction,maintains, and sedation during surgery. Propofol also reduces cerebal blood flow, maintain rate for oxygen and decreased intracranial pressure. This literature review identify the benefits and safety of cerebral hemodynomic use of Ketamine versus propofol for induction in the adult population showing for decompressive craniotomy.There were currently researches , studies and reviews is 31 give conclusion /outcome is decreased ICP ,hemodynamic control , and ideal pain control. Appear use of ketamine does not increase ICP and may be just producing the desired result for those showing with TBI.