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Stream/Area:
-
Subject:
-
Paper ID:
IJSREM65213
Volume:
10 |
6 |
Jun 2026
Pages:
1-11
Publication Frequency:
Monthly (12 issues per year)
License:International Journal of Scientific Research in Engineering and Management follows the Creative Commons Attribution 4.0 (CC BY 4.0) License, allowing free use and distribution with proper attribution.
Department of biotechnology
Shiv chhatrapati college, Dr Babasaheb Ambedkar University
Department of biotechnology
Shiv chhatrapati college, Dr Babasaheb Ambedkar University
Department of biotechnology
Shiv chhatrapati college, Dr Babasaheb Ambedkar University
Department of biotechnology
Shiv chhatrapati college, Dr Babasaheb Ambedkar University
Department of biotechnology
Shiv chhatrapati college, Dr Babasaheb Ambedkar University
Department of biotechnology
Shiv chhatrapati college, Dr Babasaheb Ambedkar University
Department of biotechnology
Shiv chhatrapati college, Dr Babasaheb Ambedkar University
The present study focuses on the formulation and application of a CMC-based hydrogel enriched with Tridax procumbens leaf extract for wound healing and fruit-coating purposes. Carboxymethyl cellulose (CMC), known for its biocompatibility, moisture retention ability, and gel-forming properties, was cross-linked with citric acid to develop a stable hydrogel system. Tridax procumbens, a medicinal herb with proven antimicrobial, anti-inflammatory, antioxidant, and wound-healing properties, was incorporated into the hydrogel to enhance its therapeutic potential. Phytochemical screening of the leaf extract confirmed the presence of flavonoids, tannins, saponins, and terpenoids, which contribute to antimicrobial and regenerative activities. The hydrogel was prepared, homogenized, and incubated to allow proper infusion of plant bioactive compounds. The formulated gel was tested for antibacterial activity, showing effective inhibition against selected microbial strains. Additionally, the hydrogel was evaluated for fruit-coating efficiency, demonstrating its ability to prevent spoilage and maintain freshness. Overall, the study concludes that CMC hydrogel enriched with Tridax procumbens extract is a promising natural biomaterial with significant potential in wound healing applications and biodegradable fruit preservation. The combination of CMC and medicinal plant extract provides a safe, eco-friendly, and effective alternative to synthetic gels and chemical preservatives.
KEYWORDS
• It was concluded that leaf extract of Tridax procumbens possesses the antimicrobial property against the bacterial samples checked for, E. coli and S. aureus. • The clear zones were observed around the Tridax procumbens sample loaded in the culture media, which indicates the growth inhibition of the bacteria. • The fruits coated with Tridax procumbens hydrogel preservative coating remained fresh and healthy for 8 days, whereas fruits without coating became stale.
1. Aniel, Kumar, O., & Naidu, M. (2010). Antibacterial potential of Tridax procumbens against human pathogens. Pharma Science Monitor, ISSN 0976-7908, 468–477. 2. Ayappadas, M.P., Dhanabalan, R., & Doss, A. (2009). In vitro antibacterial activity of two medicinal plants against bovine udder isolated bacterial pathogens from dairy herds. 3 Chitra, M., Devi, C.S.S., & Sukumar, E. (1994). Antibacterial activity of Tridax procumbens Linn. Indian Journal of Pharmaceutical Sciences, 56(4), 159–160. 4 Cushnie, T., & Lamb, A.J. (2005). Antimicrobial activity of flavonoids. International Journal of Antimicrobial Agents, 26, 343–356. 5. David, M.M., & Pascalia, N. (2019). Phytochemicals and antibacterial activities of leaf extract of Tridax procumbens on Staphylococcus aureus and Escherichia coli. East African Scholars Journal of Biotechnology and Genetics, 1(6), 2663–2686. 6. Jadhav, V.D., Talele, S.G., Bakliwal, A.A., & Chaudhari, G.N. (2015). Formulation and evaluation of herbal gel containing Tridax procumbens. Journal of Pharma and Bio Sciences, 3(2), 165–171. 7.Laxmi, & Begum, T. (2022). Phytochemical analysis of leaf extract of the medicinal plants. 8. Mohamed Sham Shihabudeen, H., Hansi Priscilla, D., & Kavitha, T. (2010). Antimicrobial activity and phytochemical analysis of selected Indian folk medicinal plants. International Journal of Pharmaceutical Sciences and Research, 1, 430–434. 9.Mohamed Sham Shihabudeen, H., Hansi Priscilla, D., & Kavitha, T. (2010). Antimicrobial activity and phytochemical analysis of selected Indian folk medicinal plants. International Journal of Pharmaceutical Sciences and Research, 1, 430–434. 10.Nur Fitrah, N., Zainuddin, N., & Ahmad, M. (2019). Department of Chemistry, Faculty of Science, University Putra Malaysia, 43400 UPM, Serdang, Selangor.
Publication Date
6/20/2026
Peer Review Type
Double-Blind Peer Review
Review Rounds: 2
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