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ArticlePeer ReviewedOpen AccessPlagiarism Passed
Paper ID:IJSREM63563

DRUG DISCOVERY STRATEGIES USING DEEP LEARNING MODELS

Stream/Area:

-

Subject:

-

Paper ID:

IJSREM63563

Volume:

10 |

5 |

May 2026

Pages:

1-4

Publication Frequency:

Monthly (12 issues per year)

DOI
Digital Object Identifier
Not assigned

License:International Journal of Scientific Research in Engineering and Management follows the Creative Commons Attribution 4.0 (CC BY 4.0) License, allowing free use and distribution with proper attribution.

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Authors

RP

Revathi Patel

MASTER OF COMPUTER APPLICATIONS

BAPUJI INSTITUTE OF ENGINEERING AND TECHNOLOGY DAVANGERE

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APM

Anusha P M

MASTER OF COMPUTER APPLICATIONS

BAPUJI INSTITUTE OF ENGINEERING AND TECHNOLOGY DAVANGERE

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Abstract

Ensemble Intelligence in Systems Pharmacology: In the traditional systems pharmacology and drug development paradigm, the pipeline is challenged by the issue of high attrition rates and very high research and development expenses, especially within the final phases of assessment in terms of safety and efficacy, of candidate entities. Our proposed project offers a solution to the mentioned bottleneck issue by leveraging the use of the Ensemble AI Framework which is forecasted to provide predictions with respect to pharmacologic outcomes and high dimensional Multi-Omics data. The process of drug discovery is a lengthy, resource-intensive, and expensive procedure usually dependent on high-throughput screening, combinatorial chemistry, and empirical verification. The structure-based drug discovery method utilizes deep learning tools that analyze protein-ligand interactions, while generative deep learning algorithms like VAE and GAN aid de novo drug discovery by generating novel chemical compounds with desired traits.

KEYWORDS

KEYWORDS: Drug discovery Deep learning AI Ensemble AI framework Multi-Omics Data RNN GNN Biological Data.

Cite This Article

Revathi Patel, Anusha P M, "DRUG DISCOVERY STRATEGIES USING DEEP LEARNING MODELS," International Journal of Scientific Research in Engineering and Management, vol. 10, no. 5, pp. 1-4, May 2026.

Full Article/Conclusion

The R&D Drug Discovery System using an Ensemble AI Framework demonstrates the potential of integrating multi-omics data with advanced deep learning and ensemble techniques to deliver a reliable and intelligent solution for predicting drug efficacy and toxicity. By combining multiomics integration with predictive modeling, the system improves the performance and precision of preclinical drug assessment compared to traditional experimental methods. laboratory testing, this framework provides faster and datadriven insights, reducing both research costs and time.. The platform’s modularity ensures a high degree of Domain Versatility, making it a viable asset for enterprise pharmaceutical R&D, academic bio-foundries, and precision clinical environments. It establishes a new benchmark for computational pharmacology where the acceleration of lead-compound prioritization directly correlates to reduced clinical attrition and optimized resource allocation. Finally, incorporating multimodal data combining omics with chemical, imaging, or clinical datasets could enhance predictive performance and reduce false. Accuracy in this system typically ranges between 85% to 95%, depending on the dataset quality and model used.

References

Ballard, J. L., Wang, Z., Li, W., Shen, L., & Long, Q. (2024). Deep learning-based approaches for multi-omics data integration and analysis. BioData Mining, 17(38). Cheng, Z., Yan, Q., Ding, D., & Ding, Y. (2025). A scalable and robust ensemble deep learning method applied for predicting drugtarget interactions. Interdisciplinary    Sciences: Computational Life Sciences. Wang, Y., Yang, Y., Chen, S., & Wang, J. (2021). DeepDRK: A deep learning kernel-based multi-omics integration framework for drug repurposing. Briefings in Bioinformatics, 22(5), bbab048. Zitnik, M., Agrawal, M., & Leskovec, J. (2018). A graph convolutional network approach to modelling polypharmacy side effects. Bioinformatics, 34(13), i457–i466. Chen,       H.,    Engkvist,        O., Wang, Y., Olivecrona, M., & Blaschke, T. (2018). The growth of deep learning within drug discovery. Drug Discovery Today, 23(6), 1241–1250. Ching, T., Himmelstein, D. S., BeaulieuJones, B. K., et al. (2018). Opportunities and obstacles for deep learning in biology and medicine. Journal of The Royal Society Interface, 15(141), 20170387. Ghosh, S., Mollah, M. N. H., & Hasan, M. (2020). A review on deep learning in drug discovery. Computers in Biology and Medicine, 123, 103843.. Zhang, W., Chen, Y., Liu, F., et al. (2021). Predicting drug–disease associations by integrating multi-omics data with graph neural networks. Briefings in Bioinformatics, 22(5), bbab045.

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Publication Date

5/20/2026

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Double-Blind Peer Review

Review Rounds: 2

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