Formulation & Evaluation of Aqueous Guava & Babul Leaves for the Treatment of Mouth Ulcer

Formulation & Evaluation of Aqueous Guava & Babul Leaves for the Treatment of Mouth Ulcer

Hitesh Kumar 1, Seema Kashyap1*, Rajesh Kumar Nema1,

Harish Sharma2, Gyanesh Kumar Sahu1

1 Rungta Institute of Pharmaceutical Sciences

2 Rungta Institute of Pharmaceutical Sciences & Research

Corresponding Author:

Mrs Seema Kashyap

Associate Professor

Email ID: kashyapseema85@gmail.com

ABTRACT

This study delved the development and evaluation of a new herbal gel for mouth ulcers using pulverized guava leaves. The gel incorporated colorful attention of the leaves with Carbopol 934 and Propylene glycol as a base. Evaluation included assessments of the gel's physical parcels and natural exertion. Infrared spectroscopy verified no adverse commerce between the leaves and the gelatinizing agent. The performing gel was transparent, invariant, and had a neutral pH range( 7- 7.5). also, it demonstrated good rheological parcels, spreading and banishing fluently. Anti- fungal tests revealed significant effectiveness against Candida albicans and Aspergillus aureus. In vitro analysis verified the presence of flavonoids in the guava leaves, contributing to their potent antioxidant exertion. This suggests implicit for combating oxidative stress associated with mouth ulcers. The formulated gel offered a stable, safe, and potentially superior volition to conventional synthetic treatments for mouth ulcers. Its overall parcels suggest a promising advancement in this area. In conclusion, the herbal gel displayed a range of desirable characteristics- translucency, unity, good rheology, potentanti-fungal exertion, and significant antioxidant parcels. These findings place it as a potentially safe and effective herbal remedy for mouth ulcers, potentially outperforming being synthetic options.

Keywords- Guava Leaves Powder, Gel, Mouth Ulcer, antioxidant, mucosal layer.