Formulation of a Herbal Cream for the Management of Psoriasis

Psoriasis is a chronic inflammatory and immune-mediated skin disorder characterised by erythema, scaling, itching, and hyperproliferation of keratinocytes. Long-term use of conventional therapies such as topical corticosteroids and systemic immunosuppressants is often associated with adverse effects, creating a need for safer therapeutic alternatives. Herbal formulations have gained significant attention due to their improved safety profile and therapeutic efficacy. Calendula officinalis, Glycyrrhiza glabra (liquorice), and Ocimum sanctum (tulsi) are well-known medicinal plants possessing anti-inflammatory, antioxidant, antimicrobial, immunomodulatory, and wound-healing properties that are beneficial in the management of psoriasis. The present review highlights the pharmacological potential of these herbal drugs and their role in the formulation of a topical herbal cream for psoriasis management. Emphasis is given to formulation aspects, mechanism of action, and evaluation parameters of the herbal cream, along with its advantages over conventional topical therapies. The review concludes that a herbal cream containing calendula, liquorice, and tulsi may serve as a promising, effective, and safe approach for the topical management of psoriasis.