Herbal Approach in the Treatment of Polymorphous Light Eruption Through Topical Cream Formulation

Polymorphous light eruption (PMLE) is the most common, idiopathic, acquired photodermatosis, characterized by abnormal, recurrent, and delayed reaction to sunlight. Polymorphous light eruption is common worldwide but the morphology, distribution, and pigmentary changes are unique in Indian skin which is discussed in this review. The prevalence of PMLE is around 10–20% in the general population. It commonly occurs in females between 20and 30 years of age. Herbal substances may work as adsorbents of the UV rays and antioxidants and potentially have few side effects. Many of them have shown the potential to protect from UV rays. Among the most studied herbal substances that have proven photoprotective activity are Polypodium leucotomos extract (PLE). Most of the Indians belong to type IV to type VI skin and pigmentary changes are commonly seen. The unique feature of PMLE in Indian skin is the pigmentary change which varies from hypopigmented to hyperpigmented lesions.