Injectable Drug Product Formulation

This study has been undertaken to investigate the Parenteral Formulations are sterile, pyrogen-free, administered by injection through skin layers. This review highlights all the aspects regarding parenteral products advantages, disadvantages, routes of administration, additives, preparation, types of containers and quality control tests for evaluation. They are required, like any pharmaceutical dosage forms, to meet the pharmaceutical quality standards as described in pharma-copeias and to be safe for the intended purpose of use. Sterility can be achieved by different processes of sterilization that should be appropriate to the formulations, while the pyrogen-free aspect will require, if no depyrogenation process is used during the preparation of the sterile drug products, the use of pyrogen-free pharmaceutical ingredients; drug substances or API (Active Pharmaceutical Ingredient) and excipients.