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Paper ID:IJSREM63362

MediCare-Agent: A Multi-Agent AI System for Post-Discharge Nephrology Patient Care Using LangGraph, RAG, and Large Language Models

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-

Subject:

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Paper ID:

IJSREM63362

Volume:

10 |

5 |

May 2026

Pages:

1-6

Publication Frequency:

Monthly (12 issues per year)

DOI
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Not assigned

License:International Journal of Scientific Research in Engineering and Management follows the Creative Commons Attribution 4.0 (CC BY 4.0) License, allowing free use and distribution with proper attribution.

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P

PRINCE

DEPARTMENT OF ARTIFICIAL INTELLIGENCE AND DATA SCIENCE

DR AKHILESH DAS GUPTA INSTITUTE OF PROFESSIONAL STUDIES

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RC

RITESH CHANDEL

DEPARTMENT OF ARTIFICIAL INTELLIGENCE AND DATA SCIENCE

DR AKHILESH DAS GUPTA INSTITUTE OF PROFESSIONAL STUDIES

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Abstract

Post-discharge care represents a critical gap in the healthcare journey of patients with chronic kidney conditions. Patients discharged from nephrology departments often struggle with unanswered clinical queries, complex medication regimens, and uncertainty about symptom severity — challenges that contribute significantly to preventable hospital readmissions. The proposed MediCare-Agent is an AI-driven, multi-agent system designed to provide 24/7 intelligent post-discharge support to nephrology patients. Built using a stateful LangGraph 0.2.28 workflow, the system routes patient queries through a four-node agent pipeline comprising a Router Node, Patient Identification Node, Medical Consultation Node, and General Response Node. Medical queries are answered using Retrieval-Augmented Generation (RAG) over a 1,547-page Comprehensive Clinical Nephrology textbook indexed via FAISS-cpu, with query results personalized using patient-specific context retrieved from a SQLite database. A locally hosted HuggingFace all-MiniLM-L6-v2 embedding model generates 384-dimensional dense vectors for semantic retrieval, while Meta's Llama 3.3 70B — served through Groq's free inference tier — powers all natural language generation and intent classification. A seven-entry nephrology drug reference database and DuckDuckGo real-time web search provide supplementary knowledge without any API key or subscription cost. Developed using FastAPI on the backend and Streamlit on the frontend, the system delivers structured, triage-formatted medical responses with end-to-end latency of approximately 3–4 seconds at zero monthly operational cost. This paper demonstrates how open-weight LLMs, domain-specific retrieval, and multi-agent orchestration can be combined into a deployable, patient-facing post-discharge care system.

KEYWORDS

Abbreviations AI: Artificial Intelligence API: Application Programming Interface CKD: Chronic Kidney Disease eGFR: Estimated Glomerular Filtration Rate FAISS: Facebook AI Similarity Search JWT: JSON Web Token LLM: Large Language Model NLP: Natural Language Processing PDF: Portable Document Format RAG: Retrieval-Augmented Generation REST: Representational State Transfer SQLite: Self-Contained Lightweight SQL Database Engine UUID: Universally Unique Identifier

Cite This Article

PRINCE, RITESH CHANDEL, "MediCare-Agent: A Multi-Agent AI System for Post-Discharge Nephrology Patient Care Using LangGraph, RAG, and Large Language Models," International Journal of Scientific Research in Engineering and Management, vol. 10, no. 5, pp. 1-6, May 2026.

Full Article/Conclusion

The MediCare-Agent system demonstrates the transformative potential of multi-agent AI in the domain of post-discharge nephrology patient care. By leveraging LangGraph, FAISS-indexed RAG, Groq-hosted Llama 3.3 70B, SQLite patient management, and DuckDuckGo real-time search, the project achieved its goal of building a clinically structured, personalized, and fully zero-cost post-discharge support system. Features such as patient-context query enhancement, structured triage classification, mandatory medical disclaimers, and a three-step hierarchical routing strategy effectively address the limitations of general-purpose chatbots in clinical patient-facing applications. The system delivers GPT-4-class response quality at 3–4 seconds end-to-end latency with no recurring infrastructure cost — a property critical for adoption in resource-constrained healthcare settings.   Future enhancements will focus on integration with HL7 FHIR-compliant Electronic Health Record (EHR) systems for real-time patient record access, replacing the current static SQLite database. A formal randomized controlled clinical trial with real nephrology patients will be conducted to obtain quantitative accuracy, patient satisfaction, and health outcome metrics. Multi-source RAG augmentation incorporating PubMed abstracts, KDIGO clinical guidelines, and FDA drug label data will broaden knowledge coverage. Streaming token responses will reduce perceived latency. Voice interface support will improve accessibility for elderly patients with limited digital literacy. A longitudinal analytics dashboard tracking patient symptom trends and medication adherence will provide clinicians with population-level post-discharge insights.

References

[1] GBD Chronic Kidney Disease Collaboration, "Global, regional, and national burden of chronic kidney disease, 1990–2017: A systematic analysis for the Global Burden of Disease Study 2017," The Lancet, vol. 395, no. 10225, pp. 709–733, Feb. 2020. [2] Shortliffe, E. H. and Cimino, J. J. (2014). Biomedical Informatics: Computer Applications in Health Care and Biomedicine, 4th Edition, Springer. [3] Lee, J. et al. (2020). BioBERT: A Pre-trained Biomedical Language Representation Model for Biomedical Text Mining. Bioinformatics, vol. 36, no. 4, pp. 1234–1240. [4] Singhal, K. et al. (2023). Large Language Models Encode Clinical Knowledge. Nature, vol. 620, pp. 172–180. [5] Touvron, H. et al. (2023). Llama 2: Open Foundation and Fine-Tuned Chat Models. arXiv preprint arXiv:2307.09288. [6] Lewis, P. et al. (2020). Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks. Advances in Neural Information Processing Systems (NeurIPS), vol. 33, pp. 9459–9474. [7] Zakka, C. et al. (2024). Almanac — Retrieval-Augmented Language Models for Clinical Medicine. NEJM AI, vol. 1, no. 2. [8] Johnson, J., Douze, M., and Jégou, H. (2021). Billion-Scale Similarity Search with GPUs. IEEE Transactions on Big Data, vol. 7, no. 3, pp. 535–547. [9] LangChain Inc. (2024). LangGraph: Building Stateful, Multi-Actor Applications with LLMs. Documentation v0.2.28. Available: https://langchain-ai.github.io/langgraph [10] Reimers, N. and Gurevych, I. (2019). Sentence-BERT: Sentence Embeddings Using Siamese BERT-Networks. Proceedings of EMNLP, pp. 3982–3992.

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Publication Date

5/17/2026

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