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ArticlePeer ReviewedOpen AccessPlagiarism Passed
Paper ID:IJSREM44050

One Pot Synthesis of Dihydropyrano (2,3-c) pyrazoles Catalyzed by Bronsted Acid

Stream/Area:

-

Subject:

-

Paper ID:

IJSREM44050

Volume:

9 |

4 |

Apr 2025

Pages:

Publication Frequency:

Monthly (12 issues per year)

DOI
Digital Object Identifier
10.55041/ijsrem44050

License:International Journal of Scientific Research in Engineering and Management follows the Creative Commons Attribution 4.0 (CC BY 4.0) License, allowing free use and distribution with proper attribution.

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Authors

PY

P. Yaswanthi

L

L.Nagakiran

D

Dr.N.KrishnaRao

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Abstract

An efficient and versatile multicomponent procedure for the synthesis dihydropyrano (2, 3-c) pyrazole derivatives promoted by Bronsted Acid as a catalyst is PTSA in protic solvent and These derivatives can be obtained series of dihydropyrano (2,3-c)pyrazoles from ethyl acetoacetate, hydrazine hydrochloride, malononitrile, and aromatic  aldehydes in the presence of PTSA. This method was is used for environmentally friendly multicomponent cyclocondensation methods  which have a series of  intriguing advantages , including the use of a nontoxic solvent, inexpensive and readily available catalyst, simplicity in work-up, high yields (up to 91%). The compound can be confirmed by 1HNMR, 13CNMR and LCMS. Besides, the study of the antimicrobial activity was against bacterial as well as fungal strains.

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Cite This Article

P. Yaswanthi, L.Nagakiran, Dr.N.KrishnaRao, "One Pot Synthesis of Dihydropyrano (2,3-c) pyrazoles Catalyzed by Bronsted Acid," International Journal of Scientific Research in Engineering and Management, vol. 9, no. 4, Apr 2025. https://doi.org/10.55041/ijsrem44050

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4/8/2025

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Review Rounds: 2

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