Overview of Acne, their Biochemical Relevance and Roles in Skin Health

Acne is a chronic inflammatory skin disorder that impacts both physical appearance and mental health in people of all ages. Niacinamide, or vitamin B3, has drawn interest recently as a potential supplementary or alternative treatment for acne because of its anti-inflammatory, antioxidant, and sebum-regulating qualities. This review’s objective is to assess niacinamide’s efficacy in treating acne by examining clinical research, its mode of action, and its safety profile. Several studies have shown that topical niacinamide can enhance skin barrier function, lessen inflammation, and lessen the severity of acne lesions without causing the irritation that more severe therapies do. Niacinamide is also a possible treatment for post-inflammatory hyperpigmentation because it has been demonstrated to improve skin repair. The data currently in favor of using niacinamide to treat acne is summarized in this review.