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Paper ID:IJSREM66641

Phytochemical Screening and Antimicrobial Study on Euphorbia Hirta Plant Extracts

Stream/Area:

-

Subject:

-

Paper ID:

IJSREM66641

Volume:

10 |

8 |

Aug 2026

Pages:

1-3

Publication Frequency:

Monthly (12 issues per year)

DOI
Digital Object Identifier
Not assigned

License:International Journal of Scientific Research in Engineering and Management follows the Creative Commons Attribution 4.0 (CC BY 4.0) License, allowing free use and distribution with proper attribution.

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Authors

GM

Gowtham M

Pharmacy

SRI Vijay Vidhyalaya College of Pharmacy

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Elangovan K

Elangovan K

Pharmacy

SRI Vijay Vidhyalaya College of Pharmacy

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EK

Elavarasan K

Pharmacy

SRI Vijay Vidhyalaya College of Pharmacy

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GP

Gayathri P

Pharmacy

SRI Vijay Vidhyalaya College of Pharmacy

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Abstract

Euphorbia hirta L. (family Euphorbiaceae), commonly known as asthma weed or “tawa-tawa,” is a widely distributed medicinal herb traditionally used to treat asthma, bronchitis, dysentery, diarrhoea, and skin infections. The present study was undertaken to carry out phytochemical screening and to evaluate the antimicrobial potential of successive solvent extracts (petroleum ether, chloroform, ethanol and aqueous) of the whole plant of Euphorbia hirta. The shade-dried and powdered plant material was subjected to extraction, and the resulting extracts were screened for the presence of major phytoconstituents such as alkaloids, flavonoids, tannins, saponins, glycosides, steroids, terpenoids and phenolic compounds using standard qualitative chemical tests. The antimicrobial activity of the extracts was assessed by the agar well diffusion method against selected Gram-positive, Gram-negative bacteria and a fungal strain, and the zones of inhibition were compared with standard antibiotic and antifungal controls. The results confirmed the presence of clinically relevant secondary metabolites and demonstrated measurable antimicrobial activity, particularly in the ethanolic extract, supporting the traditional use of this plant and its potential as a source of lead compounds for the development of new antimicrobial agents.

KEYWORDS

Euphorbia hirta Phytochemical screening Antimicrobial activity Agar well diffusion Secondary metabolites Zone of inhibition.

Cite This Article

Gowtham M, Elangovan K, Elavarasan K, Gayathri P, "Phytochemical Screening and Antimicrobial Study on Euphorbia Hirta Plant Extracts," International Journal of Scientific Research in Engineering and Management, vol. 10, no. 8, pp. 1-3, Aug 2026.

Full Article/Conclusion

The present study demonstrates that Euphorbia hirta contains a wide array of pharmacologically important secondary metabolites, and its extracts – particularly the ethanolic extract – possess significant antimicrobial activity against common bacterial and fungal pathogens. These findings lend scientific support to the traditional use of Euphorbia hirta in the management of infectious conditions and suggest its potential as a source for the development of new, plant-derived antimicrobial agents. Further studies involving isolation and characterization of the active constituents, along with in-vivo evaluation and toxicity studies, are recommended to fully establish its therapeutic potential.

References

[1] Kokate C.K., Purohit A.P., Gokhale S.B., “Pharmacognosy,” Nirali Prakashan, Pune, 50th ed., 2016. [2] Khandelwal K.R., “Practical Pharmacognosy – Techniques and Experiments,” Nirali Prakashan, Pune, 29th ed., 2019. [3] Kirtikar K.R., Basu B.D., “Indian Medicinal Plants,” International Book Distributors, Dehradun, 2nd ed., Vol. 3, 1991. [4] Ogueke C.C., Ogbulie J.N., Okoli I.C., Anyanwu B.N., “Antibacterial activities and toxicological potentials of crude ethanolic extracts of Euphorbia hirta,” Journal of American Science, vol. 3, no. 3, pp. 11–16, 2007. [5] Ogbulie J.N., Ogueke C.C., Okoli I.C., Anyanwu B.N., “Antibacterial activities and toxicological potentials of crude ethanolic extracts of Euphorbia hirta,” African Journal of Biotechnology, vol. 6, no. 13, pp. 1544–1548, 2007. [6] Sharma N., Samarakoon K.W., Gyawali R., et al., “Evaluation of the antimicrobial, antioxidant and anti-inflammatory activity of Euphorbia hirta,” Plants, vol. 3, pp. 380–393, 2014. [7] Perumal Samy R., Ignacimuthu S., Sen A., “Screening of 34 Indian medicinal plants for antibacterial properties,” Journal of Ethnopharmacology, vol. 62, pp. 173–182, 1998. [8] Harborne J.B., “Phytochemical Methods – A Guide to Modern Techniques of Plant Analysis,” Chapman & Hall, London, 3rd ed., 1998. [9] Trease G.E., Evans W.C., “Pharmacognosy,” W.B. Saunders, London, 15th ed., 2002. [10] CLSI, “Performance Standards for Antimicrobial Disk Susceptibility Tests,” Clinical and Laboratory Standards Institute, Wayne, PA, 13th ed., 2018.

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Publication Date

8/10/2026

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Double-Blind Peer Review

Review Rounds: 2

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