Loading article...
Loading article...
Stream/Area:
-
Subject:
-
Paper ID:
10.55041/IJSREM22992
Volume:
7 |
6 |
Jun 2023
Pages:
Publication Frequency:
Monthly (12 issues per year)
License:International Journal of Scientific Research in Engineering and Management follows the Creative Commons Attribution 4.0 (CC BY 4.0) License, allowing free use and distribution with proper attribution.
A simple, rapid, accurate, economical and precise UV/VIS method has been developed and validated. Choices of a common solvent were essential so various solvent ranges including methanol, ethanol, acetonitrile, and 0.1 N HCL, and various concentrations ranges of various buffers were analyzed. Hence 0.1 N HCL was selected as a solvent for the proposed method. Caffeine and Pioglitazone HCL showed maximum absorbance at 273 and 220 nm respectively. Both drugs obey Beer Lambert’s law in the concentration range of 3-18 μg/mL for Caffeine and Pioglitazone HCL respectively. The LOD and LOQ were found to be 0.5476 μg/mL and 1.6594 μg/mL for Caffeine respectively. For Pioglitazone HCL the LOD and LOQ values were found to be 0.6111 μg/mL and 1.8519 μg/mL respectively. The method was quantitatively evaluated in terms of linearity, precision, precision, LOD, LOQ and recovery. The method is simple, convenient and suitable for the analysis of Caffeine and Pioglitazone HCL in bulk drugs.
KEYWORDS
Publication Date
7/5/2023
Peer Review Type
Double-Blind Peer Review
Review Rounds: 2
Documents
Article Views
0
Total views since publication
PDF Downloads
1
Total downloads since publication
Geographic Reach
5
Digital Preservation: This article is permanently archived on Zenodo and complies with all data preservation standards across major indexing platforms.
Plagiarism Screening
This manuscript has been checked for plagiarism using TurnitinPlagiarismChecker software.
Conflict of Interest
The authors declare no conflict of interest related to this research work.
Funding Information
No funding information available for this research.
Related research in the same subject area
Loading similar articles...