Synergistic Bilayered Gummies with L-Theanine and Vitamin D for Anxiety Relief: A Review

Anxiety disorders are among the most prevalent mental health conditions worldwide, motivating interest in complementary nutraceutical interventions. L-theanine, an amino acid found in tea leaves, and vitamin D, a secosteroid hormone critical to brain function, both demonstrate potential anxiolytic effects through distinct neurobiological pathways. This review evaluates the evidence for their individual and combined roles in anxiety relief, and explores the rationale for a bilayered gummy formulation to enhance delivery and compliance in therapeutic settings.