SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF SILVER NANOPARTICLES: SYSTEMATIC REVIEW
Pitambri Thakur 1, Jai Kumar 2, Rahul Hakhu3
1Associate Professor, University Institute of biotechnology, Chandigarh University, Gharuan, Punjab, India. E-mail: pitambri.e5316@cumail.in
2Student, University Institute of biotechnology, Chandigarh University, Gharuan, Punjab, India. E-mail: jai00345@gmail.com
3Associate Professor, Centre for Distance and Online Education, Chitkara University, Punjab, India. E-mail: drrahulhakhu@gmail.com
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Abstract - Silver is exploited for the benefit of mankind from past centuries. Silver has been proved to be much more powerful when compared to other metallic nanoparticles, not only bactericidal properties but it is also effective against eukaryotic microorganisms and viruses. Creation of Ag Nanoparticles has increased the silver efficacy many folds due to their physical and chemical properties, especially the surface area to volume ratio is most important imparting the antibacterial activity over various microorganisms. To lessen bacterial infections in incurable wounds nanocrystalline silver dressings, creams, gels are formulated. However, several problems are associated with the use. Silver nanoparticle toxicity is a major threat associated with their use and the inhibition of beneficiary microorganisms due to lack of specificity of silver nanoparticles is environmentalist’s concern. To reduce the threats associated, there should be a careful assessment of the silver nanoparticles release into the environment and should be regulated. It has to be noted that novel methods to produce silver nanoparticles which reduce the toxicity and other associated threats has to be developed in the future to exploit the vast capabilities of the silver nanoparticles for the benefit of mankind. As technology advancement is always in demand with changing environmental conditions, the present review will focus on the synthesis and antibacterial properties of silver nanoparticles along with its environmental impact.
Key Words: Silver nanoparticles ∙ Antibacterial Activity ∙ Microorganisms ∙ Environmental Impact
