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© 2026 IJSREM – International Journal of Scientific Research in Engineering and Management. This is an open-access journal. Articles are published under the Creative Commons Attribution (CC BY 4.0) License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Paper ID:10.55041/IJSREM17039

The antioxidant role of decaffeinated green coffee extract against rotenone induced parkinsonism in rats

Stream/Area:

-

Subject:

-

Paper ID:

10.55041/IJSREM17039

Volume:

6 |

12 |

Dec 2022

Pages:

Publication Frequency:

Monthly (12 issues per year)

DOI
Digital Object Identifier
10.55041/IJSREM17039

License:International Journal of Scientific Research in Engineering and Management follows the Creative Commons Attribution 4.0 (CC BY 4.0) License, allowing free use and distribution with proper attribution.

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Authors

SAD

Selvaraj Aruna Devi

RS

Ravi Surya

AJT

Arokiyasami Justin Thenmozhi

TM

Thamilarasan Manivasagam

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Abstract

Caffeine offered to have anti-cancer, neuroprotective, anti-atherosclerosis, renoprotective and hepatoprotective properties due to their mitochondrial protective, antioxidant, anti-inflammatory and anti-apoptoptic functions. But it is reported adverse effect, so the presence study aimed to study the neuroprotective role of decaffeinated green coffee extract (dGCE) rotenone induced animal model of PD by analysing TBARS and antioxidant such as SOD, catalase, GPx and GSH. Rotenone injected rat showed enhanced levels of TBARS and diminished levels and activities GSH and SOD, catalase and GPx. The study confirms the neuroprotective/antioxidant property of dGCE mainly due to the presence of chlorogenic acid (CGA) and other components of the extract.

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Cite This Article

Selvaraj Aruna Devi, Ravi Surya, Arokiyasami Justin Thenmozhi, Thamilarasan Manivasagam, "The antioxidant role of decaffeinated green coffee extract against rotenone induced parkinsonism in rats," International Journal of Scientific Research in Engineering and Management, vol. 6, no. 12, Dec 2022. https://doi.org/10.55041/IJSREM17039

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5/11/2022

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