The Biochemical Changes in Patients with Chronic Renal failure in District Hospital Shopian Jammu and Kashmir India

. This study was carried out at District Hospital Shopian to evaluate various parameters in chronic renal failure (CRF) patients, including serum urea, creatinine, lipid profile (cholesterol, triglycerides [TG], high- density lipoprotein [HDL], and low-density lipoprotein [LDL]), and thyroid hormones (free triiodothyronine [FT3], free thyroxine [FT4], and thyroid- stimulating hormone [TSH]). A total of 41 patients participated in the study, consisting of 26 males and 16 females, with ages ranging from 17 to 88 years. The control group comprised 30 individuals without any signs or symptoms of renal disease, lipid disorders, or thyroid hormone disorders, including 15 males and 10 females, with ages ranging from 22 to 66 years The study findings revealed that serum urea and creatinine concentrations were significantly higher in CRF patients compared to the control group (P0.05). There were no significant differences observed in serum cholesterol, HDL, and LDL concentrations between CRF patients and the control group. Similarly, no significant differences were found in serum FT3, FT4, and TSH concentrations between CRF patients and the control group. Furthermore, there were no significant associations identified between changes in lipid profile concentrations and changes in thyroid hormone concentrations.