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Paper ID:IJSREM59866

Automated Diabetic Retinopathy Detection Using Capsule Networks with Explainability

Stream/Area:

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Subject:

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Paper ID:

IJSREM59866

Volume:

10 |

4 |

April 2026

Pages:

1-9

Publication Frequency:

Monthly (12 issues per year)

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Not assigned

License:International Journal of Scientific Research in Engineering and Management follows the Creative Commons Attribution 4.0 (CC BY 4.0) License, allowing free use and distribution with proper attribution.

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Authors

DGNK

Dr G.Rosline Nesa Kumari

Dept. of CSE

Bharath Institute of Higher Education and Research Chennai, India

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MV

Morri Venkatesh

Dept. of CSE

Bharath Institute of Higher Education and Research Chennai, India

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MVSR

Muddam Vivek Sai Ram

Dept. of CSE

Bharath Institute of Higher Education and Research Chennai, India

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MVC

MuddamSetty Vishnu Charan

Dept. of CSE

Bharath Institute of Higher Education and Research Chennai, India

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MVVR

M Venkata Vasudeva Reddy

Dept. of CSE

Bharath Institute of Higher Education and Research Chennai, India

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Abstract

Diabetic Retinopathy (DR) is a leading cause of blindness worldwide, requiring early detection for effective treatment. Traditional deep learning models, such as Convolutional Neural Networks (CNNs), have shown promise in automating DR detection but often lack interpretability and robustness. This study proposes a novel approach by integrating Capsule Networks (CapsNets) with Explainable AI (XAI) techniques to enhance the accuracy and transparency of DR classification. The CapsNet model was trained on a diverse dataset of retinal images, achieving an accuracy of 92%, outperforming traditional CNN-based approaches in capturing spatial hierarchies and reducing misclassifications. Grad-CAM visualization was employed to highlight clinically significant regions, improving trust and interpretability in AI-driven diagnostics. The study also explores dataset expansion, model optimization, and potential clinical applications. The proposed method advances AI-driven healthcare by ensuring both high-performance and explainability, facilitating seamless integration into clinical workflows.

KEYWORDS

Keywords— Diabetic Retinopathy Capsule Networks Explainable AI Grad-CAM Deep Learning Medical Image Analysis.

Cite This Article

Dr G.Rosline Nesa Kumari, Morri Venkatesh, Muddam Vivek Sai Ram, MuddamSetty Vishnu Charan, M Venkata Vasudeva Reddy, "Automated Diabetic Retinopathy Detection Using Capsule Networks with Explainability," International Journal of Scientific Research in Engineering and Management, vol. 10, no. 4, pp. 1-9, April 2026.

Full Article/Conclusion

This paper presented an automated diabetic retinopathy detection system using a Capsule Network (CapsNet) integrated with Explainable AI techniques for retinal image analysis. The system effectively classifies DR severity levels and provides visual explanations of predictions, reducing dependency on manual diagnosis. By leveraging the spatial feature learning capability of CapsNet and the interpretability of Grad-CAM, the proposed model achieved high accuracy and reliability in DR detection tasks. The results demonstrate that the model outperforms traditional CNN and ANN-based approaches in both performance and transparency, making it highly suitable for clinical decision support systems. In the future, the system can be enhanced by incorporating larger and more diverse retinal datasets to improve generalization. The integration of advanced explainable AI techniques such as SHAP or LRP can further improve interpretability. Additionally, hybrid models combining CapsNet with other deep learning architectures can be explored to achieve even higher accuracy and robustness.  

References

[1]               [1] K. Zhang, H. Li, and Y. Liu, "Explainable Deep Learning for Microaneurysm Detection in Diabetic Retinopathy," IEEE Access, vol. 11, pp. 7894-7905, 2023. https://doi.org/10.1109/ACCESS.2023.3245501 [2]               [2] R. Patel, S. K. Singh, and P. Tiwari, "Microaneurysm Detection Using Hybrid CNN-SVM Model with Explainable AI," IEEE Journal of Biomedical and Health Informatics, vol. 27, no. 3, pp. 1332-1343, 2023. https://doi.org/10.1109/JBHI.2023.3284692 [3]               [3] T. Nguyen, M. Rodriguez, and C. Lee, "Deep Learning-Based Microaneurysm Detection in Retinal Images with Integrated Explainability," IEEE Access, vol. 12, pp. 11029-11040, 2023. https://doi.org/10.1109/ACCESS.2023.3300075 [4]               [4] A. Rahman, D. Singh, and H. Nakamura, "Attention-Based Transformer Models for Explainable Microaneurysm Detection in Retinal Images," IEEE Transactions on Artificial Intelligence, 2024. https://doi.org/10.1109/TAI.2024.3356709 [5]               [5] K. Al-Mansoori, X. Chen, and N. Ahuja, "Multi-Scale Feature Fusion with Explainable AI for Microaneurysm Detection," IEEE Transactions on Neural Networks and Learning Systems, vol. 35, no. 2, pp. 2451-2462, 2023. https://doi.org/10.1109/TNNLS.2023.3300541 [6]               [6] M. Chen, S. Patel, and R. Kumar, "Explainable AI Techniques for Robust Microaneurysm Detection Using Hybrid CNN Approaches," IEEE Transactions on Medical Imaging, vol. 43, no. 5, pp. 3225-3236, 2023. https://doi.org/10.1109/TMI.2023.3316751 [7]               [7] W. Zhang, Y. Sun, and R. Gupta, "Microaneurysm Detection in Retinal Images Using Explainable AI and Transfer Learning," IEEE Transactions on Image Processing, vol. 33, no. 8, pp. 5562-5573, 2024. https://doi.org/10.1109/TIP.2024.3356901 [8]               [8] H. Wang, F. Luo, and L. Zhang, "Explainable AI-Driven Ensemble Learning for Microaneurysm Detection in Diabetic Retinopathy," IEEE Transactions on Computational Imaging, vol. 10, pp. 159-171, 2023. https://doi.org/10.1109/TCI.2023.3349805 [9]               [9] N. Ahmed, M. Hasan, and A. Chatterjee, "A Comprehensive Review on Explainable AI for Microaneurysm Detection," IEEE Reviews in Biomedical Engineering, 2024. https://doi.org/10.1109/RBME.2024.3367809 [10]             [10] Y. Chen, X. Li, and H. Zhou, "Explainable AI-Based Microaneurysm Detection Using Deep Neural Networks," IEEE Transactions on Biomedical Engineering, vol. 71, no. 1, pp. 111-122, 2023. https://doi.org/10.1109/TBME.2023.3358701

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Publication Date

4/22/2026

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