A Review Article of Curcumin Transdermal Patch
Utkarsh R. Mandage.1*, Indrayani S. Pagare2, Anushka S. Deore3
1Lecturer, Department of Pharmacognosy, Ravindra Vidya Prasarak Mandal Institute of Pharmacy, Dwarka, Nashik, India.
2Principal, Department of QA, Ravindra Vidya Prasarak Mandal Institute of Pharmacy, Dwarka, Nashik, India.
5 Assistant Professor, Department of Pharmacognosy, MET’s Institute of Pharmacy, Adgaon, Nashik, India.
ABSTRACT
Currently herbal medications are the subject of various investigations on innovative drug delivery systems. The framework used to administer transdermal curcumin medicine was created and assessed. . Curcumin is also known as diferuloylmethane (94%) in science with molecular formula C21H2006. It comes from the subterranean stem of the Curcuma longa plant, which is naive to East India. Curcumin, the main curcuminoid in turmeric, makes up about 2-5% of the spice and contributes significantly to its therapeutic effects and distinctive yellow color. Preformulation studies, encompassing solubility, compatibility, and description investigations, were assessed of the medication curcumin. Mostly, the transdermal patches were prepared by using, a solvent evaporation method. Several Physiological and Invitro evaluation parameters are studied like thickness, weight variation,
flatness, surface pH, moisture uptake, etc. of the transdermal patches. Curcumin contains several types of pharmacological actions like anti-inflammatory, anti-fungal, anti-oxidant, anti-cancer etc. In future, curcumin is widely used in the world as a medicine like anti- oxidant property used in the formulations of cosmetic products. Curcumin's characteristics make it in high demand in both the domestic and foreign markets. In India, curcumin value of about 43 billion rupees. nhancing the bioavailability of curcumin increases its market worth. This review mainly focuses on the curcumin properties, mechanisms, enhancement of bioavailability, transdermal preparation, and their evaluation.
KEYWORDS: Curcumin, Transdermal patch, Pharmacological actions
