Assessing the Increased Risk of Myocardial Infarction in Diabetes Mellitus Patients and Strategies for Prevention
Dr.G.Susmitha 1, C.Nagamani2, K.Sumalatha3, Tayyaba Mahtab4, Dr.G.Lalith Sagar Reddy5
1Associate Professor,Dept.of Pharmacy Practice,Bhaskar Pharmacy College,Moinabad
2 Associate Professor,Dept.of Chemisytry,Bhaskar Pharmacy College,Moinabad
3 Associate Professor,Dept.of Pharmacognosy ,Bhaskar Pharmacy College,Moinabad
4 Associate Professor,Dept.of Pharmaceutical Analysis ,Bhaskar Pharmacy College,Moinabad
5Assistant Professor,Dept.of Pharmacy Practice,Bhaskar Pharmacy College,Moinabad
---------------------------------------------------------------------***---------------------------------------------------------------------
Abstract - Myocardial infarction (MI) is a leading cause of morbidity and mortality globally, with individuals suffering from diabetes mellitus (DM) facing a significantly higher risk than non-diabetic individuals. Epidemiological studies reveal that the incidence of myocardial infarction and sudden cardiac death in diabetic patients is notably elevated, particularly among females, with the risk being two-fold greater in men and up to four-fold higher in women. Moreover, silent myocardial infarction is observed more frequently in diabetic patients during autopsy compared to non-diabetics. Myocardial infarction in diabetes can be attributed to a combination of factors, including increased blood glucose levels, atherosclerosis, and thrombosis. These factors damage blood vessels and nerves that regulate heart function, accelerating the development of coronary artery disease. Individuals with diabetes are at a higher risk of experiencing heart disease at a younger age, with myocardial infarction and stroke being the leading causes of death in this population.
Preventive measures play a crucial role in reducing the risk of MI in diabetic patients. Primary prevention strategies such as controlling blood pressure, managing dyslipidemia, reducing obesity, smoking cessation, and regular physical activity have been proven to significantly lower the chances of MI. This study aims to evaluate the high risk of myocardial infarction in diabetic patients and to assess preventive measures, including pharmacological and non-pharmacological interventions. By analyzing the clinical data of 200 patients from Olive Hospitals, Hyderabad, the study intends to identify key risk factors, therapeutic strategies, and preventive steps for myocardial infarction in diabetes mellitus patients. Early detection and intervention are essential in mitigating the elevated cardiovascular risks associated with diabetes..
Key Words: Myocardial infarction, diabetes mellitus, dyslipidaemia,