Formulation and Characterization of Antimicrobial Potential of Herbal Cream using Clitoria Ternatea Linn. Flowers (Aparajita) For the Treatment of Vaginal Infection

Clitoria ternatea, a member of the Fabaceae family, is frequently referred to as butterfly pea. It is utilised in several ayurvedic preparations and is usually referred to as “Shankpushpi” in Sanskrit. In addition to its medical applications, C. ternatea flowers are used as a natural food colouring and have become increasingly popular as ornamental flowers around the world. The purpose of this study was to treat vaginal infections by creating an antifungal cream with Clitoria ternatea Linn. (Flowers). Plant parts and flowers having antifungal, antibacterial, antioxidant, and antiaging qualities are frequently found in herbal cosmetic formulations. The safest product for everyday use that doesn’t cause any negative effects is herbal cosmetics. The most prevalent gynaecological issue that women encounter during their lives is vaginal infection, or vaginitis, which is brought on by Candida species. The current study aims to investigate the plant’s anti-candida properties. The creation of a herbal cream was also the goal. The aqueous extract of Clitoria ternatea Linn. flowers was used in the formulation and evaluation of the herbal cream in this study, and the results showed good results when compared to standard drugs. The herbal cream’s formulation yielded highly promising and great outcomes compared to other herbal creams.  In order to uncover and demonstrate the effectiveness of a prepared dosage form, it is crucial to ensure biological activity for every formulation. In light of this, herbal creams were made and tested for anti-candida properties; the cream’s anti-candida activity was assessed as an ideal preparation. The PHC (HC5) has the best anti-candida activity when compared to the conventional formulation (MCC), according to the data, and can be used to treat vaginal infections. Furthermore, thorough clinical methods must be established in order to manufacture safe and efficient medications.