Topical Nanoemulgel for Treatment of Psoriasis

Topical Nanoemulgel for Treatment of Psoriasis

Ms. Waghmare K.R. 1, Dr. Chaus W. N. 2

1 Lecturer, Dayanand Institute of Pharmacy, Latur.

2 Principal, Dayanand Institute of Pharmacy, Latur.

ABSTRACT: India has a rich tradition of plant based knowledge of healthcare. Modern pharmaceutical technology is being combined with traditional health medicine to increase its efficacy. Psoriasis is a chronic inflammatory disease that affects 1–3% of the all-inclusive community with significant hindrance to the personal quality of life. These conditions may adversely affect the patient’s quality of life and prompt psychosocial stretch. Psoriasis can be classified as mild, moderate, and severe conditions. Dermal treatment guaranteeing percutaneous penetration is presently very suggested in topical signs for psoriatic patients, which can be accomplished utilizing pharmaceutical Nanoparticles i.e., Nanoemulgel formulation. For topical drug delivery, poor permeability of drugs leads to a high cost of therapy and decreased patient compliance. This problem can be controlled by preparing lipid-based colloidal sub-micron drug delivery. Due to this technique concentration of drugs can be penetrated the skin as the lipophilic intracellular pathway of the skin allows penetration of materials of less than 20nm; hence drug repository is created in the stratum corneum and epidermis. This review aims to prepare Herbal Nanoemulgel containing psoraliya corylifolia.

KEYWORD: Bakuchi (psoraliya corylifolia), Antipsoriatic activity, Topical Nanoemulgel