Anti-Inflammatory Activity of Green Synthesized Jasmine Oil Medicated Silver Nanoparticles
Bharathi Krishnan S 1, Kotteeswaran K 2 Raziya Mehar S 3 , Sabitha k 4 , Rithika shree J 5
Running Title: Anti-Inflammatory Potential of Green-Synthesized Jasmine Oil-Mediated Silver Nanoparticles.
Affiliation:
1,3,4,5 Under Graduate Student, Saveetha College of Physiotherapy, Saveetha Institute of Medical and Technical Science, Chennai, Tamil Nadu, India-602105
2 Professor, Saveetha College of Physiotherapy, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu
ABSTRACT :
INTRODUCTION:
Inflammation is a natural immune response, but chronic inflammation contributes to various diseases. Jasmine oil has anti-inflammatory properties, and silver nanoparticles (AgNPs) are known for their antimicrobial and healing effects. This study explores the anti-inflammatory potential of green-synthesized AgNPs using jasmine oil.
METHODS:
Jasmine oil and silver nitrate were combined to create silver nanoparticles, as shown by a color shift. To produce nanoparticles, the mixture underwent centrifugation and ultrasonication. The BSA Denaturation Assay was used to evaluate for anti-inflammatory action. Jasmine oil AgNPs (10–50 µL) were combined with BSA, heated, and their absorbance was measured at 660 nm. Assay for Egg Albumin: Samples containing egg albumin were heated, and the absorbance at 660 nm was measured. Diclofenac sodium served as the standard.
RESULTS :
AgNPs made from green-synthesised jasmine oil shown dose-dependent anti-inflammatory action by lowering denaturation of proteins. Absorbance decreased in the BSA assay from 0.151 (10 µL) to 0.081 (30 µL), with a minor rise at 40 µL (0.118). The readings in the egg albumin assay dropped from 0.44 (10 µL) to 0.153 (40 µL). These results validate the produced nanoparticles' ability to reduce inflammation.
CONCLUSION:
Green-synthesized jasmine oil AgNPs displayed effective anti-inflammatory activity, supporting their potential use in natural wound healing and skin care applications.
KEYWORDS :
Mandarin oil, inflammation, anti-inflammatory activity and silver nano particles
